Which clinical history findings are characteristic of immune thrombocytopenia (ITP) in children?

Updated: Jan 11, 2020
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

In children, most cases of ITP are acute, and onset seems to occur within a few weeks of recovery from a viral illness. The severity of symptoms of the viral illness does not correlate with the degree of thrombocytopenia.

Thrombocytopenia is a recognized complication after infection with Epstein-Barr virusvaricella viruscytomegalovirusrubella virus, or hepatitis virus (AB, or C). However, the most typical association is with a vaguely defined viral upper respiratory infection or gastroenteritis.

Transient thrombocytopenia has been reported to be associated with recent immunization with attenuated live-virus vaccines. [36, 37]


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