How does the incidence of immune thrombocytopenic purpura (ITP) vary by age?

Updated: Jun 28, 2019
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

Children may develop ITP at any age, but the incidence peaks in children aged 1-6 years. [30] Adults may be affected at any age, but most cases are diagnosed in women aged 30-40 years.

Onset in a patient older than 60 years is uncommon, and a search for other causes of thrombocytopenia is warranted. The most likely causes in these persons are myelodysplastic syndromes, acute leukemia, and marrow infiltration (myelophthisis). Persons with ITP who are 70 years or older are at increased risk for spontaneous bleeding and treatment-related adverse events. [31]


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