How is immune thrombocytopenic purpura (ITP) diagnosed?

Updated: Jun 28, 2019
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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No single laboratory result or clinical finding establishes a diagnosis of ITP; it is a diagnosis of exclusion. The differential diagnosis includes such other causes of thrombocytopenia as leukemia, myelophthisic marrow infiltration, myelodysplasia, aplastic anemia, and adverse drug reactions. Pseudothrombocytopenia due to platelet clumping is also a diagnostic consideration.

For discussion of ITP in pregnancy, see Immune Thrombocytopenia and Pregnancy. For patient education information, see the First Aid and Injuries Center, as well as Bruises.

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