Which medications in the drug class Immunosuppressants; Antineoplastics, Antimetabolite; DMARDs, Immunomodulators are used in the treatment of Hodgkin Lymphoma?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

Immunosuppressants; Antineoplastics, Antimetabolite; DMARDs, Immunomodulators

Antimetabolite antineoplastic agents interfere with cell functions by competing for its receptors or enzymes involved in the synthesis of DNA. Tissues that have a high rate of cellular metabolism are most sensitive to the effects.

Methotrexate (Rheumatrex, Trexall)

Methotrexate is an antimetabolite that inhibits dihydrofolate reductase, which is necessary for conversion of folate to biologically active tetrahydrofolate.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!