What are the treatment options for advanced Hodgkin lymphoma (Hodgkin disease) with and without bulky disease?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

In general, the following guidelines may be helpful when treating advanced-stage Hodgkin lymphoma:

  • Advanced stage without bulky disease: ABVD for six (occasionally eight) cycles, no routine radiation therapy. Acceptable alternatives would be BEACOPP or Stanford V

  • Advanced stage bulky disease: ABVD for six cycles with involved-field radiation therapy to original sites of bulky disease (generally 30-36 Gy). Acceptable alternatives would be BEACOPP or Stanford V


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