When is the Stanford V regimen used in treatment of advanced Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

For patients with an IPS score of less than 3, the NCCN suggests use of the Stanford V regimen. [4] This regimen is used by some clinicians because of its decreased length of treatment and decreased doses of agents. Initial single-institution studies showed impressive results, [81] but subsequent randomized trials have not shown superiority over ABVD. [82]

Although these data suggest that ABVD remain the standard treatment for most patients, the Stanford V regimen may be appropriate for those patients in whom lower doses of bleomycin and doxorubicin are desired, or in those in whom radiation is going to be administered regardless of therapy response.


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