What are the commonly used chemotherapy regimen for advanced Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The most commonly used regimen, and one endorsed by the National Comprehensive Cancer Network (NCCN), is ABVD (doxorubicin [Adriamycin], bleomycin, vinblastine, dacarbazine). [4, 74, 75] The drugs are administered every 14 days, with one cycle consisting of two administrations. This regimen is most commonly given for up to six cycles (12 doses of chemotherapy), although, occasionally, eight cycles are used. It is important to give the doses as planned (maintenance of dose intensity), and it should be noted that afebrile neutropenia is not a reason to withhold therapy. [76]


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