How are the ABVD and A+AVD regimens administered in Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The ABVD regimen is given every 28 days for six or more cycles, as follows:

  • Doxorubicin: 25 mg/m 2, days 1, 15
  • Bleomycin: 10 mg/m 2, days 1, 15
  • Vinblastine: 6 mg/m 2, days 1, 15
  • Dacarbazine: 375 mg/m 2, days 1, 15

The A+AVD regimen is given every 28 days for six cycles, as follows:

  • Brentuximab vedotin: 1.2 mg/kg, days 1, 15
  • Adriamycin: 25 mg/m 2, days 1, 15
  • Vinblastine: 6 mg/m 2, days 1, 15
  • Dacarbazine: 375 mg/m 2, days 1, 15

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