What is the Stanford V regimen for treatment of Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The Stanford V regimen is a multidrug regimen with irradiation included as part of standard therapy. [55] The drugs are administered weekly, alternating myelosuppressive and nonmyelosuppressive agents, for 12 weeks. Involved-field radiation (IFRT) at the conclusion of the 12-week treatment is an important part of this regimen. A potential advantage of the Stanford V regimen is that its use of a broad spectrum of chemotherapy drugs can limit the exposure (and potential side effects) of any single drug. However, several studies have failed to show superiority over ABVD, and the latter regimen remains the standard. [56]


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