How are treatment response criteria defined for Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Treatment response criteria are defined as follows:

  • Complete remission (CR): Disappearance of all evidence of disease as assessed by computed tomography (CT) scanning, positron-emission tomography (PET) scanning, history and physical examination, and bone marrow biopsy (if appropriate)

  • Partial response: Achievement of at least a 50% regression in sites of measurable disease and no new sites of disease

  • Stable disease: Failure to achieve either of the above criteria, but not meeting criteria for progressive disease

  • Progressive disease: Any new lesion or an increase from a nadir of at least 50% in a measurable lesion; if this occurs after a prior CR, it is called relapsed disease


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