What is prognosis of Hodgkin lymphoma (Hodgkin disease)?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

Patient prognosis is largely based on the stage of the disease and various prognostic factors, which may be defined differently across various major cooperative groups (eg, German Hodgkin's Study Group [GHSG] vs European Organisation for Research and Treatment of Cancer [EORTC] and others). [29] (See also Staging.)

The SEER data report an 86.2% overall 5-year survival rate from 2006-2012. [22] Table 1 summarizes the stage distribution and 5-year relative survival at diagnosis for the same period for all races and both sexes. [22] In addition to the stage of the disease, many factors contribute to the likelihood of survival from Hodgkin lymphoma (see Staging). Factors that influence prognosis include patient age, presence or absence of B symptoms, stage of disease, and elevation of erythrocyte sedimentation rate. [30]

Table 1. Stage Distribution and 5-Year Relative Survival by Stage at Diagnosis for All Races and Both Sexes: 2011-2015 (Open Table in a new window)

Stage at Diagnosis

Stage Distribution, %

5-year Relative Survival, %

Stage I  (only in originating layer of cells)

15

92.3

Stage II  (confined to primary site)

40

93.4

Stage III (spread to regional lymph nodes)

21

83.0

Stage IV (cancer has metastasized)

20

72.9

Unstaged

4

82.7

Source:  National Cancer Institute. SEER stat fact sheets: Hodgkin lymphoma. Available at: http://www.seer.cancer.gov/statfacts/html/hodg.html. Accessed: September 12, 2018


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!