How are the radiation fields used in the treatment of Hodgkin lymphoma (Hodgkin disease) defined?

Updated: Sep 12, 2018
  • Author: Bradley W Lash, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Published guidelines from the National Comprehensive Cancer Network (NCCN), [4] the European Society for Medical Oncology (ESMO), [5] and the International Harmonization Project [6] provide consensus opinions from leading experts on evidence-based approaches to the diagnosis and treatment of Hodgkin lymphoma. See Guidelines.

 

The radiation fields used in the treatment of Hodgkin lymphoma are generally defined as follows:

  • Involved-field radiation (IFRT): Radiation field that encompasses all of the clinically involved regions (eg, the mediastinum and the low-supraclavicular fields)

  • Involved-site radiation (ISRT): Radiation field that includes pre- and post-chemotherapy nodal volumes plus a 1.5-cm margin of healthy tissue; ISRT is largely replacing IFRT

  • Involved-node radiation (INRT): Radiation field that includes pre- and post-chemotherapy nodal volumes plus a 1-cm margin of healthy tissue


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