How is alloimmune thrombocytopenia in neonates treated?

Updated: Nov 30, 2019
  • Author: Perumal Thiagarajan, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

Answer

If left untreated, alloimmune thrombocytopenia in neonates persists from a few days to up to 3 weeks. The treatment of choice is the administration of IVIG and maternally compatible platelets. Maternal platelets should be radiated to avoid graft versus host disease in the infant, and washed to reduce the antibody concentration. Response to steroids is rare. [8]


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