What is the epidemiology of platelet disorders?

Updated: Nov 30, 2019
  • Author: Perumal Thiagarajan, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

Answer

Inherited hemostatic disorders are relatively rare. The prevalence of von Willebrand disease has been estimated at 1 case per 1000-5000 population.

In contrast, acquired hemostatic disorders are common, and ITP is one of the most common autoimmune disorders. The acute self-limiting form of ITP, which is observed almost exclusively in children, occurs at a rate of 5 cases per 100,000 population, and the chronic form, which is observed mostly in adults occurs at a rate of 3-5 cases per 100,000 population.

Unlike hemophilia, most inherited disorders of platelets are not X-linked, and they are equally distributed in both sexes. Acute ITP is also observed equally in both sexes. Chronic autoimmune thrombocytopenia is more common in females than in males.


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