What are the manifestations of thrombotic thrombocytopenic purpura (TTP)?

Updated: Nov 30, 2019
  • Author: Perumal Thiagarajan, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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TTP is a rare but serious disorder that was initially described as having a pentad of manifestations, as follows:

  1. Thrombocytopenia (with purpura)
  2. Red blood cell fragmentation
  3. Kidney failure
  4. Neurologic dysfunction
  5. Fever

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