What is the role of smoking cessation medications in the development of suicidal behaviors?

Updated: Sep 25, 2018
  • Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD  more...
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Answer

Answer

Moore et al determined that the risk of depression and suicidal or self-injurious behaviors is substantially increased and statistically significant with the use of varenicline. Risk was also present, but smaller, with bupropion, and was even smaller with nicotine replacement. The investigators suggested that varenicline is unsuitable as a first-line agent to aid in smoking cessation. [8]


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