What are the organism-specific therapeutic regimens for Klebsiella pneumoniae acute bacterial exacerbation of chronic bronchitis (ABECB)?

Updated: Jul 22, 2021
  • Author: Jazeela Fayyaz, DO; Chief Editor: John J Oppenheimer, MD  more...
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Amoxicillin/clavulanate 875/125 mg PO BID for 7-10 days or

Cefuroxime 250-500 mg PO BID for 10 days or

Levofloxacin 500 mg PO q24h for at least 7 days or

Moxifloxacin 400 mg PO q24h for 5 days or

Ciprofloxacin 500 mg PO for 10 days or

Trimethoprim-sulfamethoxazole (160 mg/800 mg) 1 DS tablet PO q12h for 10-14 days

IV formulated antibiotics include: ceftriaxone, gentamicin, amikacin, aztreonam, piperacillin/tazobactam, and imipenem/cilastatin.

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