What are the organism-specific therapeutic regimens for Mycoplasma pneumoniae and Chlamydophila pneumoniae acute bacterial exacerbation of chronic bronchitis (ABECB)?

Updated: Jul 22, 2021
  • Author: Jazeela Fayyaz, DO; Chief Editor: John J Oppenheimer, MD  more...
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Macrolides and tetracyclines are drugs of choice:

  • Azithromycin 500 mg PO on day 1 then 250 mg on days 2-5 alternatively 500 mg PO daily for 3 days or

  • Erythromycin 400 mg PO QID for 10 days or

  • Clarithromycin 250-500 mg PO BID for 7-14 days or

  • Doxycycline 100 mg PO BID for 5 days or

Less active are fluoroquinolones:

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