What are the indications for organism-specific therapy for cellulitis?

Updated: Apr 15, 2021
  • Author: Alfred Scott Lea, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Once microorganisms are identified based on cultures, treatment is tailored to the patient’s needs. The most common offenders (beta-hemolytic streptococci, MSSA, MRSA) are discussed in Cellulitis Organism-Specific Therapy.

Empiric therapy in patients with 'complicated' cellulitis involving specific clinical situations (ie, marine exposure, fresh water exposure, nonhuman mammalian bites, human bitesdiabetic foot wounds, recurrent cellulitis, facial cellulitis/erysipelas/periorbital cellulitis, surgical site infections, immunosuppressive states, and necrotizing cellulitis/Fournier gangrene)  are more difficult and are not treated as 'uncomplicated cellulitis'.

Unusual forms of SSTI (ie, clostridial myonecrosispyomyositiscutaneous anthraxerysipeloidglanderstularemiaplague, and bacillary angiomatosis), are discussed in separate Medscape topics.

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