What are the outpatient treatment recommendations for cellulitis without purulent drainage or abscess (nonpurulent cellulitis)?

Updated: Apr 15, 2021
  • Author: Alfred Scott Lea, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

Outpatient treatment recommendations (MRSA prevalent) are as follows:

  • Doxycycline or minocycline 200 mg PO followed by 100 mg PO q12h*

  • Trimethoprim-sulfamethoxazole (160 mg/800 mg) 1-2 tabs PO q12h*

  • Linezolid 600 mg PO q12h*§

  • Clindamycin 300-600 mg PO q6-8h*∞

  • Dalbavancin - 1.5 mg/kg x 1, or Oritavancin - 1200 mg IV x 1 (may avoid hospitalization in more severe cases)§


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