What is the International Staging System (ISS) for multiple myeloma?

Updated: Sep 12, 2018
  • Author: Mohammad I Abu Zaid, MBBS; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

ISS stages are as follows:

  • Stage I: Serum beta-2 microglobulin <  3.5 mg/L and serum albumin ≥3.5 g/dL
  • Stage II: Not stage I or stage III
  • Stage III: Serum beta-2 microglobulin ≥ 5.5 mg/L

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