What are the treatment recommendations for high-grade soft tissue sarcoma?

Updated: Apr 29, 2019
  • Author: from Memorial Sloan-Kettering - Mrinal M Gounder, MD; Chief Editor: Edwin Choy, MD, PhD  more...
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Tumors in this stage can be > 5-10 cm and have a high risk of recurrence and potential metastases

For patients with resectable disease, surgery followed by radiation therapy with or without adjuvant chemotherapy or surgery alone is recommended; preoperative radiation therapy, chemotherapy, or chemoradiation prior to surgery are alternatives in select clinical situations

Patients with unresectable disease should be treated with definitive radiation therapy, chemotherapy, or definitive chemoradiation [2, 3, 4, 5, 6]

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