What are the treatment recommendations for low-grade soft tissue sarcoma?

Updated: Apr 29, 2019
  • Author: from Memorial Sloan-Kettering - Mrinal M Gounder, MD; Chief Editor: Edwin Choy, MD, PhD  more...
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Surgery is the primary treatment for stage I sarcoma; it is considered adequate when margins are > 1 cm or if the fascia is still intact [1]

Re-resection or adjuvant external beam radiation therapy (XRT) is recommended to prevent local recurrence or if margins are < 1 cm or when location complicates resection at the time of recurrence

Radiation therapy is associated with decreased local recurrence but not necessarily with improved overall survival

Definitive radiation therapy is recommended for patients who are not surgical candidates; radiation doses range from 70-80 Gy

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