What are the treatment protocols for prostate cancer following post-radical prostatectomy recurrence?

Updated: Dec 29, 2020
  • Author: Winston W Tan, MD, FACP; Chief Editor: E Jason Abel, MD  more...
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Answer

Answer

See the list below:

  • Defined as a detectable PSA that increases on two subsequent measurements or a PSA that fails to fall to undetectable levels

  • Best PSA threshold unknown but probably between 0.2 and 0.4 ng/mL [24]
  • PSA that fails to fall to undetectable levels after prostatectomy may indicate residual prostate cancer or prostate cancer

  • Treatment options include salvage radiation therapy, androgen deprivation, and surveillance

  • Adjuvant radiation therapy may be more beneficial than salvage radiation therapy in men with poor pathologic features [2, 3]


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