How is relapsed multiple myeloma treated in patients who have received a stem cell transplantation?

Updated: Dec 31, 2018
  • Author: Sara J Grethlein, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Recommendations are as follows:

  • A second (tandem) autologous stem cell transplant is recommended for patients who relapse more than 12 mo after the first transplant (normally, enough cells are collected and cryopreserved for a tandem transplant)

  • Patients who relapse within 12 mo of the initial transplant are best treated with agents they have not received before

  • Patients who relapse after the second autologous transplant may be candidates for allogeneic transplant or salvage chemotherapy [2, 21, 22]


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