How is relapsed hairy cell leukemia treated?

Updated: Jan 16, 2019
  • Author: Sandy D Kotiah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Patients may relapse after initial treatment, so it is important to administer a second cycle of treatment as that can lead to another remission.

Although pentostatin and cladribine provide responses in greater than 85% of patients, and a median progression-free survival of up to 15 years, alternative treatments (eg, the addition of rituximab [15] ) are needed for patients whose disease becomes refractory to these treatments.


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