Which factors affect treatment selection in diffuse large B-cell lymphoma (DLBCL)?

Updated: Jun 12, 2019
  • Author: Francisco J Hernandez-Ilizaliturri, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Treatment recommendations for patients with diffuse large B-cell lymphoma (DLBCL) begin with evaluating the extent of the disease, performance status of the patient, and histologic subtypes. Treatment of localized and advanced disease varies considerably.

Below is a general treatment algorithm for DLBCL, followed by treatment recommendations for different stages of disease and for relapsed or refractory disease. [1, 2, 3]

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