What are treatment protocols for accelerated-phase chronic myelogenous leukemia (AP-CML)?

Updated: Oct 23, 2019
  • Author: Rossa Khalaf, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

TKIs are recommended as first-line treatment for patients with newly diagnosed AP-CML

In patients with disease progression to AP-CML while on TKI therapy, an alternate TKI will be beneficial as a bridge to allogeneic HCT

Omacetaxine is an option for patients with disease progression to AP-CML on TKI therapy


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