How is complete hematologic response monitored in chronic myelogenous leukemia (CML) taking TKIs?

Updated: Oct 23, 2019
  • Author: Rossa Khalaf, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

CHR is defined by the following:

  • Normalization of blood count, with white blood cell count <10,000/μL and platelet count <450,000/μL
  • Normal peripheral blood smear with no immature cells (eg, promyelocytes, myelocytes, blasts)
  • Absence of disease symptoms and palpable splenomegaly

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