What is the prevalence of plasma cell lesions?

Updated: Oct 14, 2019
  • Author: Lesley Elizabeth Fox, MD; Chief Editor: Francis H Gannon, MD  more...
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An estimated 32,110 new cases of plasma cell myeloma were expected to be diagnosed in the United States in 2019, [7] with a median age at diagnosis of 69 years. [8] This disease can occur in younger individuals but is rarely seen before the age of 45 years. [6] In addition, plasma cell myeloma occurs more commonly in Americans of African descent than of European descent. [9] There is also a slight male preponderance (male-to-females ratio, about 1.5:1). [1, 6]

Solitary plasmacytoma of bone comprises 3-5% of all plasma cell neoplasms. It is also seen more commonly in males than females but presents in a younger patient than those with plasma cell myeloma, with a median age at diagnosis of 55 years. [1]

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