What is the role of leukapheresis in the treatment of acute lymphoblastic leukemia (ALL)?

Updated: Oct 23, 2019
  • Author: Karen Seiter, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Answer

Answer

Patients with a markedly elevated WBC count, especially >100,000/mm3, are at risk for leukostasis

Symptoms include dyspnea due to pulmonary infiltration and altered mental status due to CNS effects; patients should receive emergency leukapheresis to rapidly reduce the WBC count


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