What is the role of leukapheresis in the treatment of acute lymphoblastic leukemia (ALL)?

Updated: Jul 02, 2021
  • Author: Karen Seiter, MD; Chief Editor: Matthew C Foster, MD  more...
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  • Patients with a markedly elevated WBC count, especially >100,000/mm3, are at risk for leukostasis

  • Symptoms include dyspnea due to pulmonary infiltration and altered mental status due to CNS effects; patients should receive emergency leukapheresis to rapidly reduce the WBC count

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