Which regimen has improved the prognosis of mature B-cell acute lymphoblastic leukemia (ALL)?

Updated: Jul 02, 2021
  • Author: Karen Seiter, MD; Chief Editor: Matthew C Foster, MD  more...
  • Print


See the list below:

  • Mature B-cell ALL is characterized by a high proliferative index, very high LDH, and strong CD20 positivity

  • The prognosis of mature B-cell ALL is poor when disease is treated with traditional ALL regimens

  • However, the prognosis has improved with the use of cyclical dose-dense chemotherapy that includes rituximab and aggressive intrathecal prophylaxis [15]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!