What are the treatment recommendations for Philadelphia chromosome–positive acute lymphoblastic leukemia (ALL) in patients 15 to 39 years old?

Updated: Oct 23, 2019
  • Author: Karen Seiter, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Answer

Answer

Philadelphia chromosome–positive ALL in the AYA (age 15-39 y):

  • Chemotherapy plus TKI, followed by allogeneic stem cell transplantation if an appropriate donor is available; if transplantation is not feasible, continue multiagent chemotherapy and a TKI


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