Which medications and chemical agents should patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency avoid?

Updated: Feb 19, 2019
  • Author: Srikanth Nagalla, MBBS, MS, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Patients with G6PD deficiency should avoid the following:

  • Oxidant drugs, such as the antimalarial drugs primaquine, chloroquine, pamaquine, and pentaquine

  • Nalidixic acid, ciprofloxacin, niridazole, norfloxacin, methylene blue, chloramphenicol, phenazopyridine, and vitamin K analogues

  • Sulfonamides, such as sulfanilamide, sulfamethoxypyridazine, sulfacetamide, sulfadimidine, sulfapyridine, sulfamerazine, and sulfamethoxazole

  •  Nonsteroidal anti-inflammatory drugs (NSAIDs), nitrofurantoin, and phenazopyridine

  • Isobutyl nitrite, naphthalene (moth balls), phenylhydrazine, and acetanilide

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