Which macroscopic findings are characteristic of Alzheimer disease?

Updated: Dec 23, 2019
  • Author: Thomas J Montine, MD, PhD; Chief Editor: Adekunle M Adesina, MD, PhD  more...
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Answer

Answer

AD is characterized grossly by progressive atrophy and gliosis, first of the hippocampus and medial temporal lobe, followed by other association cortices (frontal and parietal lobes), and finally by primary motor or sensory cortex (occipital lobe). [9]


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