What history suggests disseminated intravascular coagulation (DIC) and how does acutely presenting DIC manifest?

Updated: Dec 06, 2020
  • Author: Marcel M Levi, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

In addition to the symptoms related to the underlying disease process, there is typically a history of blood loss through bleeding in areas such the gingivae and the gastrointestinal (GI) system (see Table 3 below). [47] Acutely presenting DIC often manifests as petechiae and ecchymosis, along with blood loss from intravenous (IV) lines and catheters. In postoperative DIC, bleeding can occur in the vicinity of surgical sites, drains, and tracheostomies, as well as within serous cavities.

Table 3. Main Features of Disseminated Intravascular Coagulation in Series of 118 Patients (Open Table in a new window)

Features

Affected Patients, %

Bleeding

64%

Renal dysfunction

25%

Hepatic dysfunction

19%

Respiratory dysfunction

16%

Shock

14%

Central nervous system dysfunction

2%


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