How much does disseminated intravascular coagulation (DIC) increase mortality in patients with sepsis and severe trauma?

Updated: Dec 06, 2020
  • Author: Marcel M Levi, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Finally, DIC has been shown to be an independent predictor of mortality in patients with sepsis and severe trauma. [43, 44, 45, 46] The presence of DIC may increase the risk of death by a factor of 1.5 to 2.0 in various studies. An increasing severity of DIC is directly related to an increased mortality.

A study utilizing the Japanese Association for Acute Medicine (JAAM) diagnostic criteria for DIC showed that septic patients with DIC had a higher mortality than trauma patients with DIC did (34.7% vs 10.5%). [47]

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