Which assays are used for diagnosing and managing hepatitis C (HCV) infection?

Updated: Jul 29, 2019
  • Author: Joel Schifter, MD; Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

The following assays are used for diagnosing and managing hepatitis C (HCV) infection:

  • Serologic assays: These detect a specific antibody to the hepatitis C virus (anti-HCV) in the serum or plasma and are reported as a positive or a negative value

  • Molecular assays: These detect viral nucleic acid and can be qualitative or quantitative. Quantification of the virus is reported using international units per milliliter (IU/mL).

  • Genotyping assays: These are most useful in epidemiological studies and are clinically used to predict the likelihood of response and duration of therapy; they help to classify the virus into the 6 major genotypes. [1]


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