What is the goal of treatment for chronic myelogenous leukemia (CML)?

Updated: May 23, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
  • Print

The goals of treatment of chronic myelogenous leukemia (CML) are threefold and have changed markedly in the past 10 years. They are as follows:

  1. Hematologic remission (normal complete blood cell count [CBC] and physical examination (ie, no organomegaly)
  2. Cytogenetic remission (normal chromosome returns with 0% Philadelphia chromosome–positive (Ph+) cells)
  3. Molecular remission (negative polymerase chain reaction [PCR] result for the mutational BCR/ABL mRNA), which represents an attempt for cure and prolongation of patient survival

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!