How is the Ham test used to diagnose aplastic anemia?

Updated: Jan 29, 2021
  • Author: Sameer Bakhshi, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Aplastic anemia often occurs together with paroxysmal nocturnal hemoglobinuria (PNH). [58] Screening for PNH involves detection of deficiency of  glycosylphosphatidyl-inositol (GPI) anchored proteins, such as CD14, CD16 and CD24, as well as fluorescent aerolysin (FLAER) for white blood cells, and CD55 and CD59 for red cell analysis, on flowcytometry.


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