Which CBC count findings suggest aplastic anemia?

Updated: Jan 29, 2021
  • Author: Sameer Bakhshi, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Varying degrees of progressive cytopenia are observed in all three hematopoietic lineages. Reduction in platelet and leukocyte counts may precede the fall in hemoglobin. Peripheral smear is unremarkable except for the presence of mild macrocytosis. The degree of cytopenia is useful in assessing the severity of aplastic anemia. A decreased reticulocyte count is a characteristic finding.


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