When is bone marrow biopsy indicated in the workup of anemia?

Updated: Nov 26, 2019
  • Author: Joseph E Maakaron, MD; Chief Editor: Emmanuel C Besa, MD  more...
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When this group of disorders is suspected, the most important laboratory test is a bone marrow biopsy and aspiration (see Imaging and Procedures). The bone marrow biopsy permits categorization of these disorders into the following three separate groups, as shown in the image below:

  • Aplastic or hypoplastic

  • Hyperplastic

  • Bone marrow replaced with nonhematopoietic elements (infiltration of bone marrow)

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