What are the treatment guidelines for acute myeloid leukemia (AML)?

Updated: May 26, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Both the NCCN and the ESMO guidelines are in agreement with the following general recommendations for treatment [25, 112] :

  • Treatment should be given only in specialized medical centers that follow a multidisciplinary approach and that offer the possibility of enrollment in clinical trials

  • Possible curative treatments include induction chemotherapy (incorporating an anthracycline and cytarabine); post-remission (consolidation) therapy; and, in intermediate to high-risk patients, possible allogeneic stem cell transplantation

  • All-trans retinoic acid (ATRA) should be started immediately if APL is suspected

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