What are the guidelines for antibiotic prophylaxis in the management of acute myeloid leukemia (AML)?

Updated: May 26, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Prophylactic antibiotics are usually used in nonfebrile patients undergoing intensive chemotherapy. Both the National Comprehensive Cancer Network (NCCN) and Infectious Diseases Society of America (IDSA) guidelines strongly recommend antifungal prophylaxis in this group of patients. The following combination regimen is commonly used for prophylaxis:

  • Ciprofloxacin
  • Fluconazole
  • Voriconazole or posaconazole
  • Acyclovir or valacyclovir

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