Which genetic abnormalities convey a more favorable prognosis of acute myeloid leukemia (AML)?

Updated: May 26, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Genetic abnormalities that convey favorable risk are as follows:

  • t(8;21)(q22;q22.1); RUNX1-RUNX1T1
  • inv(16)(p13.1q22) or t(16;16)(p13.1;q22) ; CBFB-MYH11
  • Mutated NPM1 without FLT3-ITD or with low allelic ratio (<0.5) FLT3-ITD
  • Biallelic mutated CEBPA

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