How is abacavir hypersensitivity diagnoses?

Updated: Dec 07, 2018
  • Author: Ali Torkamani, PhD; Chief Editor: Karl S Roth, MD  more...
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Answer

Answer

Abacavir hypersensitivity remains a clinical diagnosis and can be made even when plausible alternate clinical diagnoses exist. Rash alone without additional symptoms of a systemic process (eg, fever, respiratory symptoms, gastrointestinal symptoms, malaise, or myalgias) does not suggest the presence of underlying  abacavir hypersensitivity. However, patients who develop a rash after initiating abacavir should be closely monitored for the onset of systemic symptoms. If an abacavir hypersensitivity reaction is suspected, immediately discontinue, with careful clinical follow-up. [6]  


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