What is the role of rectal submucosal biopsy in the workup of cardiac amyloidosis?

Updated: Mar 25, 2020
  • Author: Gyanendra K Sharma, MD, FACC, FASE; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Answer

Rectal submucosal biopsy has been a traditional site in the past. It has a sensitivity of greater than 75% for detecting amyloidosis but carries a risk of bleeding and rectal perforation. [72]


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