What is the role of electrophysiologic studies in the workup of cardiac amyloidosis?

Updated: Mar 25, 2020
  • Author: Gyanendra K Sharma, MD, FACC, FASE; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Answer

Electrophysiologic studies reveal the following feature:

  • Sinus and atrioventricular node functions are preserved in most patients.

  • Infra-His conduction interval is usually prolonged (> –55 ms).

  • In one study in which 23 patients who died during follow-up, infra-His prolongation was the sole independent predictor of sudden death by multivariate analysis (P = 0.05). [68]


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