What are the mortality rates of cardiac amyloidosis?

Updated: Mar 25, 2020
  • Author: Gyanendra K Sharma, MD, FACC, FASE; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Answer

Amyloidosis has a poor prognosis, and the median survival without treatment is only 13 months. Cardiac involvement has the worst prognosis and results in death in about 6 months after onset of congestive heart failure. Only 5% of the patients with primary amyloidosis survive beyond 10 years. [28] Among 82 patients with cardiac amyloidosis, New York Heart Association (NYHA) class and right ventricular systolic dysfunction (tricuspid annular plane systolic excursion [TAPSE] < 14 mm) independently predicted major adverse cardiac events. [29]


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