How is varicella-zoster (shingles) treated?

Updated: May 18, 2020
  • Author: Richard Lichenstein, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Therapy should be initiated at the earliest sign or symptom of herpes zoster and is most effective when started generally within 72h of the onset of zoster rash.

Zoster confined to dermatome (normal or immunocompromised patients):

Visceral, central nervous system, or disseminated VZV infections, and zoster in severely immunocompromised patients:

  • Acyclovir 10 mg/kg (500 mg/m2 in children < 12 y) IV q8h for 7-10d

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